Variant reclassification in cancer susceptibility genes and an updated variant spectrum of Turkish breast and colorectal cancer patients
Can ND, Akcay IM, Celik E, Ciftci C, Unal B, Agaoglu NB, Doganay HL, Dinler Doganay G.
Hum Genomics. 2026 Feb 8;20(1):39. doi: 10.1186/s40246-026-00915-0. PMID: 41656315; PMCID: PMC129180 20.

In silico-designed peptide targeting MDR1 (P-gp) restores chemosensitivity in colorectal cancer via chitosan nanoparticle delivery
Maden H, Calik H, Yilmaz Ozturk R, Ari Yuka S, Temur BZ, Can O, Dinler Doganay G, Cakir R.
J Drug Deliv Sci Technol. 2026 Mar;117:108003. doi: 10.1016/j.jddst.2026.108003.

A human pan-disease blood atlas of the circulating proteome
Bueno Álvez M, Bergström S, Kenrick J, Johansson E, Åberg M, Akyildiz M, Altay O, Sköld H, Antonopoulos K, Apostolakis E, Balcioglu YH, Bergström A, Bergström G, Björkander S, Egyhazi Brage S, Brodin P, Butler L, Cajander S, Danielsson H, Dayangac M, Dinler-Doganay G, et al.
Science. 2025 Oct 9;390(6779):eadx2678. doi: 10.1126/science.adx2678.

Layer-by-layer assembled hyaluronic acid/chitosan-coated Fe₃O₄@ rGO nanoparticles: Synthesis and characterization for doxorubicin delivery in breast cancer cells
Azmoudeh A, Sari S, Türk M, Moral S, Kaya Ö, Kahveci MU, Dinler Doganay G, Kuşcu M, Erkol Özören N, Ağaoğulları D.
Journal of Science: Advanced Materials and Devices, 2025 Dec;10(4):101012. doi: 10.1016/j.jsamd.2025.101012.

Functional analysis of MSH2 A733T variant of unknown significant mutation effect on human MutS homolog 2 (hMSH2) protein
Ciftci C, Gul CM, Can ND, Doganay L, Dinler Doganay G.
Journal of Science: Advanced Materials and Devices, 2025 Febs Open Bio. 2025 Jul 1;15:261-262.

Development of inhibitory peptides to disrupt Bag-1S: p97/VCP complex
Sahinbas G, Basturk E, Dingiloglu B, Boncuk HD, Dinler Doganay G.
Febs Open Bio. 2025 Jul 1;15:166-166.

X-ray crystallographic and hydrogen deuterium exchange studies confirm alternate kinetic models for homolog insulin monomers
Ayan E, Türk M, Tatlı Ö, Bostan S, Telek E, Dingiloğlu B, Doğan BZ, Alp MI, Katı A, Dinler-Doğanay G, Demirci H.
PLoS One. 2025 Apr 21;20(4):e0319282.

A BAG-1-inhibitory peptide, GO-Pep, suppresses c-Raf activity in cancer
Ayan E, Türk M, Tatlı Ö, Tatli O, Cebi E, Turk M, Dingiloglu B, Sezan A, Basturk E, Temur BZ, Eyupoglu AE, Bicak B, Erdal E, Erman B, Can Ö, Dinler Doganay G.
Commun Biol. 2025 Feb 28;8(1):336. doi: 10.1038/s42003-024-07419-4. PMID: 40021821; PMCID: PMC11871328.

Magnetic iron-based nanoparticles encapsulated in graphene/reduced graphene oxide: Synthesis, functionalization and cytotoxicity tests
Azmoudeh A, Moral S, Sari S, Türk M, Kahveci MU, Dinler Doganay G, Ağaoğulları D.
J Sci Adv Mater Devices. 2024 Dec;9(4):100776.

Bag-1-mediated HSF1 phosphorylation regulates expression of heat shock proteins in breast cancer cells
Kizilboga T, Özden C, Can ND, Onay Ucar E, Dinler Doganay G.
FEBS Open Bio. 2024 Sep;14(9):1559-1569. doi: 10.1002/2211-5463.13843. Epub 2024 Jul 24. PMID: 39049197; PMCID: PMC11492399.

Structural and molecular characterization of collagen-type I extracted from lamb feet
A Ata O, Bakar B, Turkoz BK, Kumcuoglu S, Aydogdu Y, Gumustas B, Doganay GD, Basturk E, Tavman S.
J Food Sci. 2024 Jan;89(1):330-341. doi: 10.1111/1750-3841.16870. Epub 2023 Dec 5. PMID: 38051022.

A two-step purification platform for efficient removal of Fab-related impurities: A case study for Ranibizumab
Tatli O, Oz Y, Dingiloglu B, Yalcinkaya D, Basturk E, Korkmaz M, Akbulut L, Hatipoglu D, Kirmacoglu C, Akgun B, Turk K, Pinar O, Sariyar Akbulut B, Atabay Z, Tahir Turanli E, Kazan D, Dinler Doganay G.
Heliyon. 2023 Oct 31;9(11):e21001. doi: 10.1016/j.heliyon.2023.e21001. PMID: 38027967; PMCID: PMC10651443.

Prenatal SARS-CoV-2 Spike Protein Exposure Induces Autism-Like Neurobehavioral Changes in Male Neonatal Rats
Erbas O, Erdogan MA, Turk M, Doganay GD, Sever IH, Ozkul B, Sogut I, Eroglu E, Uyanikgil Y.
J Neuroimmune Pharmacol. 2023 Oct 27.

Cryogenic X-ray crystallographic studies of biomacromolecules at Turkish Light Source “Turkish DeLight“
Atalay N, Akcan EK, Gül M, Ayan E, Destan E, Ertem FB, Tokay N, Çakilkaya B, Nergiz Z, Karakadioğlu G, Kepceoğlu A, Yapici İ, Tosun B, Baldir N, Yildirim G, Johnson JA, Güven Ö, Shafiei A, Arslan NE, Yilmaz M, Kulakman C, Paydos SS, Çinal ZS, Şabanoğlu K, Pazarçeviren A, Yilmaz A, Canbay B, Aşci B, Kartal E, Tavli S, Çaliseki M, Göç G, Mermer A, Yeşilay G, Altuntaş S, Tateishi H, Otsuka M, Fujita M, Tekin Ş, Çiftçi H, Durdaği S, Dinler Doğanay G, Karaca E, Kaplan Türköz B, Kabasakal BV, Kati A, Demirci H.
Turk J Biol. 2023 Jan 11;47(1):1-13. doi: 10.55730/1300-0152.2637. PMID: 37529114; PMCID: PMC10387866.

Altered kidney function induced by SARS-CoV-2 infection and acute kidney damage markers predict survival outcomes of COVID-19 patients: a prospective pilot study
Temiz MZ, Hacibey I, Yazar RO, Sevdi MS, Kucuk SH, Alkurt G, Doganay L, Dinler Doganay G, Dincer MM, Yuruk E, Erkalp K, Muslumanoglu AY.
Ren Fail. 2022 Dec;44(1):233-240. doi: 10.1080/0886022X.2022.2032743. PMID: 35172674; PMCID: PMC8856025.

Structure-based engineering of an antiangiogenic scFv antibody for soluble production in E. coli without loss of activity
Denizci Öncü M, Balcıoğlu BK, Özgür B, Öztürk HÜ, Serhatlı M, Işık Ş, Erdağ B, Dinler Doğanay G, Özdemir Bahadır A.
Biotechnol Appl Biochem. 2022 Oct;69(5):2122-2137. doi: 10.1002/bab.2273. Epub 2021 Nov 12. PMID: 34694021.

COVID-19 PCR test performance on samples stored at ambient temperature
Agaoglu NB, Yildiz J, Akgun Dogan O, Kose B, Alkurt G, Kendir Demirkol Y, Irvem A, Doganay L, Dinler Doganay G.
J Virol Methods. 2022 Mar;301:114404. doi: 10.1016/j.jviromet.2021.114404. Epub 2021 Dec 16. PMID: 34921841; PMCID: PMC8673954.

Determining the accuracy of next generation sequencing based copy number variation analysis in Hereditary Breast and Ovarian Cancer
Agaoglu NB, Unal B, Akgun Dogan O, Zolfagharian P, Sharifli P, Karakurt A, Can Senay B, Kizilboga T, Yildiz J, Dinler Doganay G, Doganay L.
Expert Rev Mol Diagn. 2022 Feb;22(2):239-246. doi: 10.1080/14737159.2022.2048373. Epub 2022 Mar 10. PMID: 35240897.

Pectin-zeolite-based wound dressings with controlled albumin release
Kocaaga B, Kurkcuoglu O, Tatlier M, Dinler-Doganay G, Batirel S, Güner FS.
Polymers. 2022 Jan 24;14(3):460.

CRISPR/Cas9-mediated Bag-1 knockout increased mesenchymal characteristics of MCF-7 cells via Akt hyperactivation-mediated actin cytoskeleton remodeling
Ozfiliz Kilbas P, Can ND, Kizilboga T, Ezberci F, Doganay HL, Arisan ED, Dinler Doganay G.
PLoS One. 2022 Jan 7;17(1):e0261062.

The comparison of differentially expressed microRNAs in Bag-1 deficient and wild type MCF-7 breast cancer cells by small RNA sequencing
Ozfiliz Kilbas P, Alkurt G, Obakan Yerlikaya P, Coker Gurkan A, Dinler Doganay G, Arisan ED.
Turk J Biol. 2022;46(2):118-136.

Recent developments in targeting RAS downstream effectors for RAS-driven cancer therapy
Tatli O, Dinler Doganay G.
Molecules. 2021 Dec 14;26(24):7561. doi: 10.3390/molecules26247561. PMID: 34946644; PMCID: PMC8703923.

Combined Metabolic Activators Accelerates Recovery in Mild-to-Moderate COVID-19
Altay O, Arif M, Li X, Yang H, Aydın M, Alkurt G, Kim W, Akyol D, Zhang C, Dinler-Doganay G, Turkez H, Shoaie S, Nielsen J, Borén J, Olmuscelik O, Doganay L, Uhlén M, Mardinoglu A.
Adv Sci (Weinh). 2021 Sep;8(17):e2101222. doi: 10.1002/advs.202101222. Epub 2021 Jun 28. PMID: 34180141; PMCID: PMC8420376.

Interactome analysis of Bag-1 isoforms reveals novel interaction partners in endoplasmic reticulum-associated degradation
Can ND, Basturk E, Kizilboga T, Akcay IM, Dingiloglu B, Tatli O, Acar S, Ozfiliz Kilbas P, Elbeyli E, Muratcioglu S, Jannuzzi AT, Gursoy A, Keskin O, Doganay HL, Karademir Yilmaz B, Dinler Doganay G.
PLoS One. 2021 Aug 24;16(8):e0256640. doi: 10.1371/journal.pone.0256640. PMID: 34428256; PMCID: PMC8384158.

Does sampling saliva increase detection of SARS-CoV-2 by RT-PCR Comparing saliva with oro-nasopharyngeal swabs
Dogan OA, Kose B, Agaoglu NB, Yildiz J, Alkurt G, Demirkol YK, Irvem A, Doganay GD, Doganay L.
J Virol Methods. 2021 Apr;290:114049. doi: 10.1016/j.jviromet.2020.114049. Epub 2020 Dec 30. PMID: 33387561; PMCID: PMC7833528.

Seroprevalence of coronavirus disease 2019 (COVID-19) among health care workers from three pandemic hospitals of Turkey
Alkurt G, Murt A, Aydin Z, Tatli O, Agaoglu NB, Irvem A, Aydin M, Karaali R, Gunes M, Yesilyurt B, Turkez H, Mardinoglu A, Doganay M, Basinoglu F, Seyahi N, Dinler Doganay G, Doganay HL.
PLoS One. 2021 Mar 3;16(3):e0247865. doi: 10.1371/journal.pone.0247865. PMID: 33657142; PMCID: PMC7928442.

Co-Chaperone Bag-1 Plays a Role in the Autophagy-Dependent Cell Survival through Beclin 1 Interaction
Turk M, Tatli O, Alkan HF, Ozfiliz Kilbas P, Alkurt G, Dinler Doganay G.
Molecules. 2021 Feb 6;26(4):854. doi: 10.3390/molecules26040854. PMID: 33561998; PMCID: PMC7914623.

Germline pathogenic variant spectrum in 25 cancer susceptibility genes in Turkish breast and colorectal cancer patients and elderly controls
Akcay IM, Celik E, Agaoglu NB, Alkurt G, Kizilboga Akgun T, Yildiz J, Enc F, Kir G, Canbek S, Kilic A, Zemheri E, Ezberci F, Ozcelik M, Dinler Doganay G, Doganay L.
Int J Cancer. 2021 Jan 15;148(2):285-295. doi: 10.1002/ijc.33199. Epub 2020 Aug 19. PMID: 32658311.

Bag-1 stimulates Bad phosphorylation through activation of Akt and Raf kinases to mediate cell survival in breast cancer
Kizilboga T, Baskale EA, Yildiz J, Akcay IM, Zemheri E, Can ND, Ozden C, Demir S, Ezberci F, Dinler-Doganay G.
BMC Cancer. 2019 Dec 28;19(1):1254. doi: 10.1186/s12885-019-6477-4. PMID: 31883527; PMCID: PMC6935482.

Hypertherophilic flavin reductase from Sulfolobus solfataricus P2: Production and biochemical characterization
Gun G, Imamoglu R, Tatli O, Yurum Y, Baykal AT, Dinler-Doganay G.
Biotechnol Appl Biochem. 2019 Nov;66(6):915-923.

Bag-1 silencing enhanced chemotherapeutic drug-induced apoptosis in MCF-7 breast cancer cells affecting PI3K/Akt/mTOR and MAPK signaling pathways
Ozfiliz Kilbas P, Akcay IM, Dinler Doganay G, Arisan ED.
Mol Biol Rep. 2019 Feb 1;46(1):847-860.

Host genetic factors affecting hepatitis B infection outcomes: Insights from genome-wide association studies
Akcay IM, Katrinli S, Ozdil K, Dinler Doganay G, Doganay L.
World J Gastroenterol. 2018 Aug 14;24(30):3347.

Identification of a BRCA2 mutation in a Turkish family with early-onset breast cancer
Celik E, Ermis Tekkus K, Akcay IM, Gizem Alkurt Sal, Ezberci F, Dinler Doganay G, Doganay L.
Clin Case Rep. 2018 Jul 17;6(9):1751.

Investigation of the role of BAG-1 in ubiquitin/proteasome system in both healthy & tumor tissues as well as cell lines in breast cancer
Acar S, Can ND, Kizilboga Akgun T, Dinler Doganay G.
Febs Open Bio. 2018 Jul 1;8:306-307.

The association of variations in TLR genes and spontaneous immune control of hepatitis B virus
Katrinli S, Nigdelioglu A, Ozdil K, Dinler-Doganay G, Doganay L.
Clin Res Hepatol Gastroenterol. 2018 Apr 1;42(2):139-144.

Bag-1 promotes cell survival through c-Myc-mediated ODC upregulation that is not preferred under apoptotic stimuli in MCF-7 cells
Ozfiliz P, Kizilboga T, Demir S, Alkurt G, Palavan-Unsal N, Arisan ED, Dinler-Doganay G.
Cell Biochem Funct. 2015 Jul;33(5):293-307.