About Us

The Dinler laboratory specializes in the molecular and structural biology of fundamental cellular processes, with a strong emphasis on the interplay between apoptosis, autophagy, and chaperone-mediated protein folding. To facilitate our research, we employ advanced biochemical techniques and structural analysis to dissect complex protein-protein interactions, specifically focusing on the signaling networks of the Bag-1 co-chaperones. Uncovering the structural details of these key regulatory proteins holds great promise for understanding cellular survival mechanisms and identifying novel therapeutic targets for cancer and related pathologies.
The overarching goals of the Dinler laboratory are to (1) operate at the interface of molecular biology, biochemistry, and structural biology to drive fundamental scientific discovery, (2) provide a vibrant and multidisciplinary research environment at Istanbul Technical University for the rigorous training of young scientists, and (3) maintain a sharp focus on translating our molecular insights into innovative biotechnological applications and potential therapeutic strategies.